Despite many technological challenges faced by the xenotransplantation field, many major advances have been made in the last two decades. The field seeks to overcome the limitations and difficulties in organ procurement, which also apply to human cells and tissues, and facilitate the development of new therapies based on cell and engineered-tissue. Xenogeneic cells are simpler than solid organs and seem to pose less hurdles to attain long-term graft survival. In, Xenotransplantation: Methods and Protocols expert researchers study characterizations of xenogeneic interactions at the cellular and molecular levels and describe the use of relevant small-animal and pig-to-primate models. Related ethical and legal considerations are also covered. Written in the highly successful Methods in Molecular Biology (TM) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.Thorough and intuitive, Xenotransplantation: Methods and Protocols aids scientists in continuing to study xenotransplantation and its multiple aspects.
In this survival guide for the new attorney, in-depth advice on law office life, includes how to work with senior attorneys, legal research, memos, drafting, mistakes, grammar, email, workload, timesheets, reviews, teamwork, deportment, attitude, perspective, working with clients (and dissatisfied clients), working with office staff, using office tools, and, well, not just surviving but thriving in a new career. This book is written for all law graduates, for any law office: a firmâlarge, medium, or smallâagency, corporation, or the military.
An indispensable guide to avoiding the legal and financial pitfalls and of retirement plan investment While it has always been true that a well-staffed and managed investment committee is key to the success of a corporate retirement plan, in today's increasingly complex and litigious world it is also a matter of survival. But what constitutes a prudent investment committee selection and operating process? How should a committee be selected and governed? How much reliance should a committee place on outside consultants? Written by an author with extensive, in-the-trenches experience, this book provides complete answers to these and all vital questions concerning the creation, staffing and management of a highly-adept investment committee, along with expert advice and guidance on serving on an investment committee and ensuring that your 401(K) investment program is sound, efficient and in complete compliance. * Offers expert advice and guidance on how to serve successfully on an investment committee, facilitate effective management, design and implement a robust investment policy and much more * Packed with sample documents, forms, templates, checklists, diagrams and other valuable, ready-to-use resources * Features numerous real-world examples drawn from the author's years of experience as an accredited investment
At last, the definitive business and legal survival kit for anyone presenting live entertainment! Everyone from performers, writers, and directors to box office managers, theater board members, and theater owners will find comprehensive answers to questions on every aspect of theater business and law. Written by an attorney and playwright, The Stage Producer's Business and Legal Guide reveals hundreds of insider strategies for minimizing legal costs, negotiating contracts, and licensing and producing plays. It also features expert, practical advice on such topics as tax risks and liabilities, safety regulations, organizing a theater company, financing, box office management, and much more! Plus, everything is explained clearly, without a lot of legal jargon.
500 businesses you can start! The time to start your own business is now! Whether you're a previously employed manager seeking new opportunities and greater job satisfaction, starting up a home-based business, re-entering the job market, or just looking to earn some extra cash on the side, this book helps you discover the business that's just right for you. This detailed reference provides more than 500 different business opportunities to choose from. Each entry features: A description of the business Start-up and hidden costs Potential earnings Qualifications and equipment needed Marketing and advertising tips for the best results In addition, this book contains critical advice on: Creating a business plan Survival strategies Legal considerations Long-term growth strategies No matter what your criteria&#8212;start-up costs, skill sets, professional and personal interests&#8212;the Adams Businesses You Can Start Almanac, 2nd Edition prepares you to take the most exciting step of your career&#8212;being your own boss!
From Erin Brockovich to Enron, whistleblowers who 'challenge abuses of power that betray the public trust' have proven to be an unfortunate necessity in modern business culture. Their efforts to report crimes, fraud, and dangers to public health and safety have saved millions of lives and billions of dollars of shareholder value - and had we heeded the warnings of whistleblowers, perhaps disasters such as the Bernie Madoff scandal and the Lehman Brothers meltdown could have been averted. Recent federal legislation in finance and health reform have cemented legal protections and mechanisms for whistleblowing. This book provides a thorough guide and history to the whistleblower's legal rights. The ultimate survival guide, it provides advice on getting help and finding allies, warns that retaliation is often the reward for 'committing the truth' and shows how to weather the storm. With extensive legal texts, sample letters, resources, and information on upcoming whistleblower reforms, this is the ultimate source on the subject.
Most technology startups never make it to the fundingstage, and only a small percentage of those that are venture-backed generate a positive return for their investors. An even smaller number of startupfounders enjoy a truly prosperous exit.Bernd Schoner cofounded his tech startup during the dot-com bust, navigated it through market crises and internal turmoil, brought it through the global financial meltdown intact, and eventually sold it to a multibillion-dollar, multinational public technology company.In The Tech Entrepreneur's Survival Guide, Berndshares what he learned and what he wished he knew at the time. He explains the major phases in a technologycompany's life cycle, helping entrepreneurs avoid common pitfalls and survive crises when they strike. He guides readers from the initial bootstrapping process through venture-capital financing and provides valuable advice on how to sell a technology company profitably--even in a challenging economic environment. Every chapter presents solutions to realworld issues that could otherwise have fatal consequences for a tech venture.Aspiring tech entrepreneurs will learn to:Set up shop: build the team, assemble necessary startup assets (including technology and intellectual property), get legal and financial affairs in orderSecure capital: ask for money, nail the term sheet, ask for more moneyGet out: know when to sell, who to sell to, and how to make it a happy exit for all stakeholders, includingthe employeesWritten with deep insight, refreshing candor, and a dash of humor, this comprehensive guide to the often harsh realities of startup life is indispensable for entrepreneurs at any stage.PRAISE FOR THE TECH ENTREPRENEUR'S SURVIVAL GUIDE:'A genuine narrative from the field, with battle scars and self-reflection. Reading this book will help you avoid many pitfalls.' -- Nicholas Negroponte, professor at the Massachusetts Institute of Technology Media Lab'There's a lot of great insights and practical advice for the entrepreneur in this book, stuff you normally won't read or hear unless you buy some hard-bitten company founder a few drinks. If you are launching a technology startup, reading this book is the thing you should do first.' -- Mark Roberti, founder and editor in chief of RFID Journal'I wish I had read Bernd's book when we founded The Echo Nest. Bernd touches on all the major issues in the initial formation stages of a tech company and many of the problems that come up when the company matures. If you are thinking of founding your own tech startup, read this book first.' -- Tristan Jehan, cofounder of The Echo Nest'A visceral, behind-the-scenes guide to technology entrepreneurship. Bernd tells it like it is and presents a universe of solutions to tricky startup situations that can significantly improve the odds of success. Indispensable.' -- Larry Begley, cofounder and managing director at .406 Ventures'The best-laid business plans never survive contact with reality. Bernd has provided a comprehensive guide to anticipating the unexpected in the life of a startup.' -- Neil Gershenfeld, professor and director of the Massachusetts Institute of Technology Center for Bits and Atoms
Practical Pharmacology for the Pharmaceutical Sciences is a lab survival guide for those studying Pharmacology, providing hands-on advice on developing pharmacology laboratory and data handling skills. Suitable for both undergraduates and postgraduates, it focuses on laboratory techniques rather than computer-simulated data. It also guides the reader through the process of communicating experimental results in a variety of formats, including posters, oral presentations and project reports. Split into three main areas, the following topics are covered in detail: Preparation for Experimental Pharmacology * Legal aspects * Fundamentals of Pharmacology * Definitions, calculations and statistics Experiments in Pharmacology * Microtitre-based techniques using isolated cells * In vitro techniques using isolated tissues and organs * Biochemical techniques using cell-free systems Communicating experimental results * Data presentation * How to write scientific reports * Pharmacological literature Supported with numerous questions throughout the text, as well as step by step instructions for practical experiments, this book presents an approach to learning pharmacology through an appreciation of authentic experimental data.
Despite many technological challenges faced by the xenotransplantation field, many major advances have been made in the last two decades. The field seeks to overcome the limitations and difficulties in organ procurement, which also apply to human cells and tissues, and facilitate the development of new therapies based on cell and engineered-tissue. Xenogeneic cells are simpler than solid organs and seem to pose less hurdles to attain long-term graft survival. In, Xenotransplantation: Methods and Protocols expert researchers study characterizations of xenogeneic interactions at the cellular and molecular levels and describe the use of relevant small-animal and pig-to-primate models. Related ethical and legal considerations are also covered. Written in the highly successful Methods in Molecular Biology&#8482; series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Xenotransplantation: Methods and Protocols aids scientists in continuing to study xenotransplantation and its multiple aspects.